If the person’s severe oesophagitis fails to respond to maintenance treatment, carry out a clinical review.Offer a full-dose PPI long-term as maintenance treatment for people with severe oesophagitis, taking into account the person’s preference and clinical circumstances (for example, tolerability of the PPI, underlying health conditions and possible interactions with other drugs), and the acquisition cost of the PPI.If initial treatment for healing severe oesophagitis fails, consider a high dose of the initial PPI, switching to another full-dose PPI or switching to another high-dose PPI, taking into account the person’s preference and clinical circumstances (for example, tolerability of the initial PPI, underlying health conditions and possible interactions with other drugs).Offer people a full-dose PPI for 8 weeks to heal severe oesophagitis, taking into account the person’s preference and clinical circumstances (for example, underlying health conditions and possible interactions with other drugs).
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